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Design of Liposome-Based Nucleus Mimic System for DNA Amplification, Pore Formation and Controlled Release of Genetic Materials

초록 (요약문)

The study of artificial cells plays an important role in understanding the functions and processes of cells. By studying artificial cells, researchers can create simplified model systems that mimic cellular components and processes to gain insight into key mechanisms and the origin of life. The nucleus is essential for overall cellular function and reproduction, which involves DNA replication and the release of genetic material to the external environment, so in this study tried to mimic the replication and release of genetic material. Advances in research have made it possible to replicate and release genetic material within artificial cells using techniques such as polymerase chain reaction (PCR) and creation of pores using pore forming materials have been studied to control the release of internal materials from artificial cells. In this study, we aim to replicate the DNA through PCR and create pores using azo lipids to mimic gene activity to perform complex mechanisms within artificial cells. We expect that this study will lead to advances in cell mimicry research and on understanding of the origin of life.

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