In-Situ Extraction of Formate in a Biocatalytic System via Ion-Pair Formation Using Quaternary Ammonium Salts under Neutral Conditions
- 주제어 (키워드) In-situ extraction , Liquid-Liquid extraction , Formate , Quaternary ammonium salts (QASs) , Ion-pair formation
- 발행기관 서강대학교 일반대학원
- 지도교수 이진원
- 발행년도 2025
- 학위수여년월 2025. 8
- 학위명 석사
- 학과 및 전공 일반대학원 화공생명공학과
- 실제 URI http://www.dcollection.net/handler/sogang/000000082082
- UCI I804:11029-000000082082
- 본문언어 영어
- 저작권 서강대학교 논문은 저작권 보호를 받습니다.
목차
1. Introduction 1
2. Material and Methods 6
2.1. Materials 6
2.2. Whole-cell biocatalyst preparation 8
2.2.1. Activity measurement 8
2.2.2. Formate productivity analysis 9
2.3. Operation of LLE extraction system 10
2.4. Analytical methods 11
2.5. Extraction parameters 12
3. Results and Discussion 14
3.1. Effect of components in the extraction system on biocatalyst stability 14
3.1.1. Organic solvents 14
3.1.2. Quaternary Ammonium Salts (QASs) 17
3.2. Evaluation of extraction performance 20
3.2.1. Time-dependent extraction kinetics 20
3.2.2. Optimization of extraction efficiency 23
3.2.3. Estimation of extraction parameters 26
3.3. Back-Extraction 28
3.4. In-Situ system validation and process feasibility 31
4. Conclusion 34
5. Acknowledgement 36
6. References 37
