과불화탄소 캡슐 버블의 제작과 크기 변화 특성
Development and Size-variation Actuation of Encapsulated Perfluorocarbon Bubble
- 주제(키워드) 과불화탄소 , 캡슐화 , 미세구동기 , ADV
- 발행기관 서강대학교 일반대학원
- 지도교수 이승엽
- 발행년도 2019
- 학위수여년월 2019. 2
- 학위명 석사
- 학과 및 전공 일반대학원 기계공학과
- 실제URI http://www.dcollection.net/handler/sogang/000000063947
- UCI I804:11029-000000063947
- 본문언어 한국어
- 저작권 서강대학교 논문은 저작권보호를 받습니다.
초록/요약
When liquid droplets or gaseous bubbles undergo repetitive size-variation by the external stimuli such as ultrasound, thermal and electrical energy, they could generate continuous micro-streaming or micro-propulsion that could transport small objects near bubbles. The size-changing bubbles have been applied for biomedical and mechanical applications such as drug delivery, medical contrast agent, micro/nano actuators and pumps. Many types of actuators including micro-swimmers or micro-pumps, activated by oscillating bubbles, had already been developed. However, the amplitude of oscillating air bubbles is only about ±3% compared to the initial size. In case of air bubbles in cylindrical tubes, the size variation is still under 10%. Therefore, the bigger size variation of bubbles by external stimuli is required to get high propulsion in miniaturized actuators. In this paper, perfluorocarbon capsule bubbles with core-shell structure are developed to cause large and repeatable size-variation using phospholipid, alginate hydrogel and PDMS. The manufactured perfluorocarbon bubble shows to increase its diameter about 60% with twelve cycles.
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