서강대학교

초록/요약

The thesis aims to realize micro/nanochannel networks in a desired position within the microfluidic systems using spatially controlled self-assembled colloids and show its versatile potential for lab-on-a-chip systems. The first objective is to fabricate and characterize the microchannel networks for a chemical molecule diffusion channel. Unlike the previous diffusion type gradient generator based on hydrogel membrane, a robust multiple chemicals concentration gradient generator is successfully presented to study the bacterial chemotactic response. This system is further utilized for the quantitative analysis of the bacterial preference for cancer secreting amino acids. The second objective is to fabricate a three dimensional ion-selective nanochannel networks between two microfluidic channels and characterize their electrokinetic phenomena by changing the geometry of the microchannel and properly selecting the size and materials of the assembled nanoparticles. Based on the understanding from these studies, the micromixer by the non-equilibrium electrokinetic is demonstrated. Moreover, the high flux ionic diode using asymmetric nanochannel networks membrane is investigated. Finally, by using the ion selective nanochannel networks, a microplatform for a power generation based on the reverse electrodialysis with half-cell is demonstrated.