1. Wolff-Kishner Reduction of Diaryl Ketones with a Solid Hydrazine 2. Preparation of Biospecific Adsorbents for cFP Receptors
- 발행기관 서강대학교 일반대학원
- 지도교수 이원구
- 발행년도 2013
- 학위수여년월 2013. 2
- 학위명 석사
- 학과 및 전공 일반대학원 화학과
- 실제URI http://www.dcollection.net/handler/sogang/000000049351
- 본문언어 영어
- 저작권 서강대학교 논문은 저작권 보호를 받습니다.
초록/요약
2.Affinity chromatography is a method of separating biochemical mixtures. It is based on a highly specific interaction such as antigen-antibody, enzyme-substrate, or receptor-ligand. MO6 is a kind of vibrio vulnificus and produces cFP. We needed a resin for receptor of cFP, and we prepared cFP resins from epoxy activated sepharose 6B and cFP analogues for affinity chromatography.
more초록/요약
1.The Wolff？Kishner reduction is a reaction that fully reduces carbonyl groups to the corresponding alkanes with hydrazine monohydrate and a base. But this reaction takes long time and has to be removed H2O halfway. We improved reaction time and also used minimum amount of reaction solvent in wolff-kishner reduction of various aromatic ketones 1 with solid hydrazine, hydrazinium carboxylate 2, instead of hydrazine monohydrate.
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